I. Basic toxicological properties
Acute toxicity
Skin/eye irritation: Liquid fluorosilicone oil is low irritant to the skin (rabbit skin irritation test score <1.0), but contact with the eyes may cause short-term mechanical irritation.
Oral toxicity: The median lethal dose (LD₅₀) of rats is >5000 mg/kg, which is practically non-toxic level 8.
Chronic exposure risk
Long-term skin contact may cause dryness or mild dermatitis, with no evidence of carcinogenicity (in accordance with OECD 452 chronic toxicity test).
Risk of pyrolysis products: Decomposition at >250℃ may release hydrogen fluoride (HF), and its concentration >3 ppm can cause respiratory damage.

‌II. Chemical stability and bioaccumulation‌
‌Evaluation dimensions‌ ‌Characteristic performance‌ ‌Safety impact‌
‌Chemical inertness‌ Tolerant to strong acids (except concentrated sulfuric acid), alkalis and oxidants, does not react with common chemicals Reduce the risk of contact poisoning
‌Biodegradability‌ Difficult to degrade in the natural environment (half-life>100 days), but no significant bioaccumulation (BCF<100) Need to prevent and control persistent environmental pollution
‌PFAS relevance‌ The preparation process does not involve PFOA/PFOS (perfluorooctanoic acid substances), which complies with the restrictions of Annex XVII of the EU REACH Regulation Avoid the risk of persistent organic pollutants

‌III. Industrial safety key control points‌
‌Operational protection requirements‌
When contacting liquid products, wear nitrile gloves and goggles, and it is recommended to use a P2-level respirator in a volatile aerosol environment.
When operating in a confined space, the concentration of fluorosilicone oil vapor must be <10 mg/m³ (OSHA recommended limit).
‌Hot processing risk prevention and control‌
Continuous use temperature should be ≤200℃. If it exceeds 204℃, HF gas adsorption device (such as alkali liquid spray tower) must be configured.

Flash point＞260℃, ignition point＞300℃, but there is still a risk of combustion in high temperature open flame environment.

IV. Environment and Compliance‌
‌Waste Disposal‌
Waste fluorosilicone oil is classified as general industrial waste (non-hazardous waste number) and must be handed over to licensed processors for high temperature incineration (＞1100℃).
‌Regulatory Standards‌
Medical-grade products must pass ISO 10993 biocompatibility test (cytotoxicity/sensitization test).
Industrial products meet the impurity limit requirements of China's "Low Viscosity Hydroxyfluorosilicone Oil" group standard (T/FSI 062-2021)