In March 30th, novel coronavirus pneumonia was novel coronavirus pneumonia in Gansu Province, and the breakthrough was made in the field of research on the new crown pneumonia. The new silicone elastomeric sampling swab was successfully developed by the backbone members of the Youth Work Committee of the Institute, Dr. Zhou Jianye of Northwest University For Nationalities and Dr. Bai Zhongtian of First Hospital Affiliated to Lanzhou University. The standardized sampling and sample pre-treatment process were specifically recommended, which is expected to enhance the new crown pneumonia. The accuracy of screening and clinical diagnosis.
The reporter has learned novel coronavirus pneumonia outbreak since the outbreak, there are false negative cases. Based on many years of experience in stomatology, basic research, laboratory medicine and laboratory verification, the team concluded that: due to the strong adsorption of mucus, it is difficult to elute the samples of flocking swabs, which leads to inadequate extraction of samples from nasopharynx and oropharynx, or may cause false negative due to low RNA content.
According to Bai Zhongtian, the main member of the research team and the winner of the 9th Youth Science and technology award of our province, during the research and development of the new sampling swab, the expert team, with the help of Gansu bolijiang 3D Printing Technology Co., Ltd. and Gansu xinbaichuan Medical Equipment Co., Ltd., cleverly designed an elastic silica sampling swab by giving full play to the advantages of interdisciplinary integration. The swab can absorb the sample with physical drainage structure and then elute the sample with elastic silica gel. It is found that the new silica gel swab can greatly increase the sampling amount compared with the existing cotton swab. Novel coronavirus pneumonia has been achieved, and further in-depth research is still in progress, which is expected to contribute to the detection of the new crown pneumonia.
Novel coronavirus pneumonia sampling and sample pretreatment procedures have not been given enough attention, and the following methods should be fully considered and standardized. According to the novel coronavirus pneumonia, the researchers made specific recommendations for the two links according to the current reports and research results of the research group, which is expected to improve the accuracy of screening and clinical diagnosis of new crown pneumonia.
Zhou Jianye and Bai Zhongtian published novel coronavirus pneumonia on the preprint (BioRxiv) online. The research report is entitled "flocking swabs may be one of the main reasons for the high false negative rate of new crown pneumonia", a new type of silica gel swabs.
It is reported that the corresponding authors of this paper are Professor Ma Zhongren, biomedical center of Northwest University for nationalities, and Professor Zhao Jin, medical department. Many authors are young backbone talents of youth working committee of Gansu bioengineering society. In addition to the co first author, the other authors are Liu Xiaoping, director of the second people's Hospital of Gansu Province, Guo Yaqiong, deputy director, Li Xiaodong, Ph.D., Institute of traditional Chinese medicine, Gansu Academy of traditional Chinese medicine, and Li Yonghong, Ph.D., Gansu people's hospital.
Founded in September 2018, the youth working committee of Gansu society of bioengineering is a scientific research group under the leadership of Gansu Association of science and technology. It aims to carry out interdisciplinary research around the characteristics and current situation of major and high incidence diseases in the western region, and actively play the characteristics of young scientific and technological workers through large-scale instrument and platform sharing, academic discussion and discipline integration, so as to organize and unite Gansu Province We have made positive contributions to clinical diagnosis and treatment and biomedicine.
Gansu science and Technology News
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