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Pharmaceutical network enterprise news
】Good news! Novel coronavirus pneumonia novel coronavirus pneumonia cases in Shanghai were also diagnosed and treated by the medical staff in the designated medical institutions, and the expert group was assessed. The assessment was in line with the forenoon of isolation and discharge criteria for the newly diagnosed coronavirus pneumonia confirmed by the national health and Health Committee, which was released this morning. So far, 140 cases have been discharged, accounting for more than 40% of the total number of confirmed cases in Shanghai. "I'm on the front line, please rest assured!" ——Li Feng, director of respiratory and critical care medicine department, Shanghai public health clinical center.
On February 14, Shanghai Lu Xiangyi
Centrifuge
Instruments Co., Ltd. has urgently supplied a batch of ground-based high-speed frozen centrifuge equipment for Shanghai public health clinical center to ensure the good operation of the equipment during the epidemic prevention period and the smooth development of targeted new coronavirus vaccine research and development.
Shanghai Public Health Clinical Center's new crown vaccine research and development was guaranteed by Lu Xiangyi to supply centrifuge equipment
There are three advantages of rapid anti new crown vaccine
Traditional vaccine research and development has always been based on the principle of virus isolation and inactivation. Although this technology is relatively mature, there are certain effectiveness and safety risks. Xu Jianqing, director of the Institute of new and reappearance infectious diseases of Shanghai public health clinical center, said that the vaccine takes human cells as the carrier, expresses the membrane protein of the virus on the human cell membrane, and puts the S protein of the new coronavirus into the human cell, which retains the effective target of antibody formation against the virus and avoids the pathogenicity of the virus itself, so it is fast and safe in general , efficient. "Maybe in a week or two, I can be a volunteer and get my own initial, ready-made vaccine." Xu told reporters with great expectation. At present, the vaccine is being tested in primates and can be used in clinical trials at any time. However, the production capacity of the follow-up small pilot scale can be achieved in about 3-4 weeks. Once the downstream industrial platform (including large-scale production facilities, process and product quality control system) is established, it can be mass produced quickly.
It takes time to fight against viruses
To recognize the virus and develop a vaccine, we need to fight against time. Why is the speed of vaccine research and development beyond normal? Zhu Tongyu first attributed it to advanced technology reserves. In novel coronavirus, the center is a professional institution that first analyzes the whole genome sequence of the new virus and announces the infectious disease to the world in Shanghai. Professor Zhang Yongzhen, director of the East China pathogen discovery and research center of the center, participated in pathogen isolation and identification earlier, and released the full genome sequence of the virus on January 10. This is the first opportunity to develop an immediate vaccine.
The novel coronavirus is not only able to withstand the existing coronavirus, but also other coronaviruses, including coronavirus in bat, will be controlled, Xu Jianqing said. If the vaccine comes out, it means that some new coronavirus will spread to people in the future, and we can actually control it. This is another focus of R & D work of public health center. "
It is reported that the center has also launched the research and development of innovative genetic engineering vaccine. "This is what we often call the nanoparticle vaccine. By assembling the viral membrane protein to form a nanoparticle, it can also ensure the speed and safety, but it may take a longer time." Xu Jianqing.
Research and development of vaccines need reliable scientific instruments
At the same time, the detection and diagnosis of new coronavirus need reliable and accurate scientific instruments, reagents and detection methods. The development of equipment performance and testing method is inseparable from the joint efforts of instrument manufacturers. Shanghai luxiangyi centrifuge instrument Co., Ltd., as a local centrifuge enterprise in Shanghai, has adopted edible grade silicone rubber integral sealing ring for its machines, According to GMP certification, silicone rubber sealing ring is tasteless and non-toxic, not afraid of high temperature and cold. It can prevent cross infection in the operation process during the experiment, and can make the relevant test data needed in the virus and epidemic situation more accurate. Lu Xiangyi Centrifuge shouldered the social responsibility of the enterprise, fully supported and cooperated with the epidemic prevention and control Targeted vaccine research and development.